Can you share your experience at NTTF?
Coating made of carbon increases the biocompatibility of medical implants
Far thinner than a hair, yet an effective barrier against cell toxins: wafer-thin layers of carbon can prevent toxins from medical implants or plastic Petri dishes from reaching the surface.
Scientists from Rheinbreitbach and Kaiserslautern produce so-called “amorphous carbon coatings” with which, for example, vascular supports or culture dishes for stem cells can be “refined”. To test to what extent the coatings meet expectations, they are cooperating with cell biologists from the University of Bonn.
Cardiologists today usually dilate narrowed coronary arteries with a balloon catheter and then support the vein with a metal tube, a stent. In order to “hide” this foreign body from the immune system, the doctors are looking for materials that can be overgrown by cells of the inner vascular wall as quickly as possible. The company NTTF - new technologies in thin films - and the institute for thin film technology in Kaiserslautern produce ultra-thin coatings from carbon with which stents and other medical implants can be "refined". Cell biologists from Bonn then examine how “biocompatible” the coated materials are: How well do skin cells grow on the “refined” stents? And do they develop as they would in the body?
Although only around 35 millionths of a millimeter thick, the coatings made of carbon prevent substances from the coated material from reaching the surface - for example metal ions or plasticizers made from plastics, which are toxic to cells. In addition, they do not react with other substances, are flexible, hard like diamonds and can be vapor-deposited onto any material. Since this is already possible at temperatures below 50 degrees, plastics can also be coated.
The Bonn cell researchers tested various coated and uncoated materials to determine the extent to which human epithelial cells, e.g. cells of the skin, can multiply and develop on them. Coated stents, for example, were evenly overgrown after a short time, while uncoated stents were hardly ever. The low temperature during the production of the coating also makes it possible to seal cell culture vessels made of plastic with thin layers. Cell cultures are very sensitive; Smallest amounts of plasticizers or other substances can interfere with their development and prevent them from dividing and multiplying. So far, cell researchers have used expensive vessels made of special plastic for their experiments. Initial tests show that coated plastic is a cost-effective alternative - human cells grew normally in the culture dishes. The process has now matured to the point where a patent has been applied for.
The scientists will present their results from November 18th to 30th during an exhibition in the Düsseldorf state parliament. Further information: www.diedrittemission.nrw.de
Professor Dr. Volker Herzog
Institute for Cell Biology at the University of Bonn
Phone: 0228 / 73-5301
Email: [email protected]
Dr. Udo Grabowy, NTTF
Tel .: 02224/968881
Email: [email protected]
All news in the category: Life Sciences Chemistry
The innovations-report offers in the field of "Life Sciences" reports and articles on applications and scientific knowledge of modern biology, chemistry and human medicine.
Among other things, you will find interesting facts from the sub-areas: bacteriology, biochemistry, bionics, bioinformatics, biophysics, biotechnology, genetics, geobotany, human biology, marine biology, microbiology, molecular biology, cell biology, zoology, bioinorganic chemistry, microchemistry and environmental chemistry.
- How clever are red-eared water turtles
- How do slats increase lift
- What is the standard hyperlink color code
- What's next for Android
- What is a Security Exchange Commission
- In what dimension is sound
- Which process is responsible for the genetic variation?
- What is the diagnosis and treatment
- Finland is part of Scandinavia
- Should I watch Supergirl TV show
- When did we start getting drunk?
- Do you need math every day
- Table salt consists only of NaCl
- Is Caroline Kennedy still married
- What are the best hostels in Vijayawada
- WHY RENT MORE IN Noida
- What was Draupadi's mother's name
- How big is Raiden
- Are SUVs cheaper than cars
- Bits Dubai is good for computer technology
- What is Dharma according to Bhagavat Gita
- Why Nifty PE is important when investing
- Why doesn't everyone just buy groceries online?
- Why are some people morning people
- How much can you believe in the story?
- How can the circulatory system be understood
- PHP variables can have numbers
- What can you do with squirrel skins?
- What's Suga's nickname
- What are some successful exhibition ideas
- Has Dahvie Vanity died
- How did Travis Kalanick fare at UCLA
- How is Workflowy